Greve SV, et al. (2016). Estimated carotid-femoral pulse wave velocity has similar predictive value as measured carotid-femoral pulse wave velocity. Journal of Hypertension, 34(7), 1279–1289.
This study validates the Greve 2 mathematical model used in VascVita to estimate pulse wave velocity (PWV), a key indicator of arterial stiffness.
Heffernan KS, et al. (2023), Estimated pulse wave velocity as a measure of vascular aging. PLoS ONE 18(1): e0280896.
This study validates the estimated pulse wave velocity (ePWV) as a simplified, high-accuracy proxy for vascular aging, enabling arterial stiffness screening using only age and blood pressure without specialized equipment.
Reference Values for Arterial Stiffness' Collaboration. (2010). Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'. European Heart Journal, 31(19), 2338–2350.
Established the definitive age- and sex-specific reference values (nomograms) for pulse wave velocity, providing the clinical gold standard to distinguish normal vascular aging from stiffness driven by cardiovascular risk factors.
Ashor AW, et al. (2014). Exercise modalities and endothelial function: a systematic review and dose–response meta-analysis of randomized controlled trials. PLOS ONE, 9(10), e110034.
Research demonstrating exercise-induced reductions in arterial stiffness, establishing the 1,000 MET-min/week threshold used in activity recommendations.
Wang H, et al. (2021). Sleep duration and arterial stiffness: a U-shaped association study linking short and long sleep durations with increased pulse wave velocity.
Established a U-shaped association between sleep duration and arterial stiffness, demonstrating that both short and long sleep durations are strongly associated with increased pulse wave velocity.